Australia's medical regulator says the current evidence does not suggest there is a link between the death of two men in New South Wales and the COVID-19 vaccine they received beforehand.
Health authorities are investigating the deaths of a 55-year-old man who died in a Tamworth hospital last week, and a 71-year-old man in Sydney, who had existing medical conditions.
Professor John Skerritt, from the Therapeutic Goods Administration, cautioned against linking vaccinations to deaths caused by blood clots.
"We have 11,000 adverse events in front of us, ranging from a sore arm through to people having a heart attack a week after having a vaccine, through to a number of other things," he told reporters on Thursday.
"For the more serious events, we certainly look at every case in detail, we discuss that with our global counterparts, and we also look to see most importantly whether there is any evidence of cause-and-effect.
"Fifty Australians a day report to hospitals or their doctors with serious blood clots from a range of activities, or from coming no reason at all. And almost all of them have no relationship to vaccination. So knowing there is a small background risk of rare blood clots is something to not hide.
"But all medicines, all treatments, all medical procedures, all activities of daily living - driving a car - flying in an aeroplane have some risk. And in the case of these vaccines, the benefits exceed the risk."
Earlier on Thursday Scott Morrison urged Australians to remain calm over the reports, saying the TGA's medical experts needed to be allowed to do their job and provide advice on all adverse reactions.
"They went through a no-corners-cut process of assessing the vaccines in Australia. Their investigators move on these issues very quickly," Mr Morrison told Darwin radio Mix 104.9 on Thursday.
"We've got to be careful about how we talk about these cases. Let's allow the medical facts to be established and let's make decisions to be made on facts."
The Prime Minister's cautious tone comes as the government and health experts try to fight rising vaccine hesitancy.
Chief Nursing Officer Alison McMillan said stringent processes were in place to investigate adverse reactions.
"It's really important not to jump to conclusions here," she told the ABC.
"We have systems to look at these deaths, unfortunate as they are."
The TGA has confirmed six cases of rare blood clots that are likely linked to the AstraZeneca vaccination.
While there is advice it not be used in people under 50, the side effect is extremely rare with between four and six cases for every one million jabs.
Victoria is putting the heat on the federal government to stump up cash for a new quarantine facility in Melbourne's north.
Treasurer Josh Frydenberg said the state government was yet to request funding.
Mr Morrison, who met with tourism industry chiefs in Darwin, said options to bring more overseas workers and international students to the NT were also being canvassed.
"It would have to be a partnership with the commercial sector," he said.
He noted setting up specific quarantine facilities like at Howard Springs near Darwin needed to consider infection control, workforce, security and flights.
"It's not just about finding a mining camp with some beds. It's much more complicated than that," the Prime Minister said.
Labor continues to pressure the coalition government to boost hotel quarantine and take charge of more federally run centres.
